Typing tool

Complete norovirus genomes

MH413070  GII.4 Hunter
 GII.P4 Hunter

Length: 7,558 | 3 CDS

ORF1: 3..5102
ORF2: 5083..6705
ORF3: 6705..7511
LOCUS       MH413070                7558 bp    RNA     linear   VRL 10-JUN-2018
DEFINITION  Norovirus GII isolate 0859, complete genome.
ACCESSION   MH413070
VERSION     MH413070.1
KEYWORDS    .
SOURCE      Norovirus GII
  ORGANISM  Norovirus GII
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus.
REFERENCE   1  (bases 1 to 7558)
  AUTHORS   Chen,H. and Hu,Y.
  TITLE     Whole-genome sequences of two human norovirus GII.4 variants
            isolated in the United States
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7558)
  AUTHORS   Chen,H. and Hu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAY-2018) Center for Food Safety and Applied
            Nutrition, Food and Drug Administration, 8301 Muirkirk Rd, Laurel,
            MD 20708, USA
FEATURES             Location/Qualifiers
     source          1..7558
                     /organism="Norovirus GII"
                     /mol_type="genomic RNA"
                     /isolate="0859"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:122929"
                     /country="USA"
                     /collection_date="08-May-2008"
                     /note="genotype: GII.4"
     gene            3..5102
                     /gene="ORF1"
     CDS             3..5102
                     /gene="ORF1"
                     /codon_start=1
                     /product="nonstructural polyprotein"
                     /protein_id="AWQ36948.1"
                     /translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARP
                     KQPPPREIPQRPPRPPTPELVKNIPPPPPNGEDEIVISYSVKDGVSGLPDLSTVRQPE
                     ESNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
                     LARVELTPLSLFWRPVYTPQYLISPDALKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
                     WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
                     LRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
                     LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
                     KKEEANELAIVRSIEDAVLDLEAIENNHMTILLKDKDSLATYMRTLDLEEEKARKLST
                     KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
                     AKRIAASLTGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
                     PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
                     AKRDFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
                     SGLLHERLDEFELQGPTLTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVRTM
                     PELKQALKNISIKKCQIVHNGCTYTLESDGKGNVKVDRVQSASVQTNNELTGALHHLR
                     CARIRYYVRCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVENTEETTGKDGC
                     PRPKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
                     KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
                     TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
                     SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
                     TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
                     CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
                     PGSAPKLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
                     RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
                     NGESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
                     ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWD
                     STQQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
                     SQWNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLR
                     EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGS
                     NHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
                     PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
     mat_peptide     3..992
                     /gene="ORF1"
                     /product="p48"
     mat_peptide     993..2090
                     /gene="ORF1"
                     /product="NTPase"
     mat_peptide     2091..2627
                     /gene="ORF1"
                     /product="p22"
     mat_peptide     2628..3026
                     /gene="ORF1"
                     /product="VPg"
     mat_peptide     3027..3569
                     /gene="ORF1"
                     /product="Pro"
     mat_peptide     3570..5099
                     /gene="ORF1"
                     /product="RdRp"
     gene            5083..6705
                     /gene="ORF2"
     CDS             5083..6705
                     /gene="ORF2"
                     /codon_start=1
                     /product="VP1"
                     /protein_id="AWQ36949.1"
                     /translation="MKMASNDATPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
                     QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
                     FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
                     VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
                     TVESRTKPFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
                     QLSPVNICTFRGDVTHIAGTQNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGRIQGVL
                     TQTTRRDGSTRGHKATVSTGSVHFTPKLGSVQFSTDTSNDFETGQNTRFTPVGVVQDG
                     STTHQNEPQQWVLPDYSGRDSHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLD
                     CLLPQEWVQHFYQESAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
                     IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
     gene            6705..7511
                     /gene="ORF3"
     CDS             6705..7511
                     /gene="ORF3"
                     /codon_start=1
                     /product="VP2"
                     /protein_id="AWQ36950.1"
                     /translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
                     SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAVN
                     APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGASSGRTNLRATVPARGSSSTPS
                     NASTATSVYSNQTASTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
                     SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN      
        1 gaatgaagat ggcgtctaac gacgcttccg ctgccgctgt tgctaacagc aacaacgaca
       61 ccgcaaaatc ttcaagtgac ggagtgcttt ctagcatggc tgtcactttt aaacgagccc
      121 tcggggcgcg gcctaagcag cctcccccga gggaaatacc acaaagaccc ccacgaccac
      181 ctactccaga actggtcaaa aatatccccc ctcccccgcc caacggagag gatgaaatag
      241 tgatttctta tagtgtcaaa gatggtgttt ccggtttgcc tgatctttcc accgtcaggc
      301 aaccggaaga atctaacacg gccttcagtg tccctccact caatcagagg gagaatagag
      361 atgctaagga gccactgact ggaacaattc tggaaatgtg ggatggagaa atctaccatt
      421 atggcctgta tgtggagcga ggtcttgtac taggtgtgca caaaccacca gctgccatta
      481 gcctcgctag ggtcgaactg acaccactct ccttgttctg gagacctgtg tatactcccc
      541 agtacctcat ctctccagac gctctcaaga aattacacgg agagacgttc ccctacacag
      601 cctttgacaa caattgctat gccttttgtt gctgggtcct ggacctaaac gactcgtggc
      661 tgagtaggag aatgatccag agaacaactg gcttcttcag gccctaccaa gattggaata
      721 ggaaacccct ccccactatg gatgactcca agttaaagaa ggtagctaac atattcctgt
      781 gtgctctgtc ttcgctattc accaggccca taaaagatat aatagggaag ctaaggcctc
      841 ttaacatcct caacatcttg gcctcatgtg attggacttt tgcaggcata gtggagtcct
      901 tgatactctt ggcagaactc tttggagttt tctggacacc cccagacgtg tctgcgatga
      961 ttgccccttt actcggtgat tacgagctac aaggacctga ggaccttgca gtggagctcg
     1021 tccctgtagt gatgggggga attggtttgg tgctaggatt caccaaagag aagattggaa
     1081 aaatgttgtc atctgctgca tccaccttga gagcttgtaa agatcttggt gcatatgggc
     1141 tagagatcct aaagttggtc atgaagtggt tcttcccgaa gaaagaggaa gcaaatgaac
     1201 tggctatagt gagatccatc gaggatgcag tcctggatct cgaggcaatt gaaaacaacc
     1261 atatgaccat cttgctcaaa gacaaagaca gtctggcaac ctacatgaga acccttgacc
     1321 ttgaggagga gaaagccagg aaactctcaa ccaagtctgc ttcacctgac atcgtgggca
     1381 caatcaacgc ccttctagcg agaatcgctg ctgcacgttc tctggtgcat cgagcgaagg
     1441 aggaactttc cagcagacca agacctgtag tgttgatgat atcaggcaga ccaggaatag
     1501 gaaagaccca ccttgctagg gaagtggcta agagaatcgc agcctccctt acaggagacc
     1561 agcgtgtagg cctcgtccca cgcaatggcg tcgaccattg ggatgcgtac aagggggaga
     1621 gggtcgtcct atgggacgac tatggaatga gcaaccccat ccacgatgcc ctcaggttgc
     1681 aagaactcgc tgacacttgc cccctcaccc taaactgtga caggattgag aataaaggaa
     1741 aggtctttga cagcgatgtc atcattatca ccactaatct ggctaaccca gcaccactgg
     1801 actatgtcaa ctttgaagca tgctcgaggc gcatcgactt cctcgtgtat gcagaagctc
     1861 ctgaggtcga aaaggcgaaa cgtgacttcc caggccaacc cgacatgtgg aagaacgcct
     1921 tcagttctga tttctcacac ataaaactaa cattggctcc acagggtggc ttcgacaaga
     1981 acgggaacac cccacacgga aagggcgtca tgaagactct caccactggc tcccttattg
     2041 cccgggcatc agggctactc catgagaggc tagatgaatt tgaactacag ggcccaactc
     2101 tcaccacctt caactttgat cgcaacaaag tgcttgcctt tagacaactt gctgctgaaa
     2161 acaaatatgg gttgatggac acaatgaaag ttgggaggca gctcaaggat gtcagaacaa
     2221 tgccagagct taaacaagca ctcaagaaca tctcaatcaa gaagtgccag atagtgcata
     2281 atggttgcac ctacacactt gagtctgatg gcaagggcaa tgtgaaagtt gacagagttc
     2341 aaagcgcctc cgtgcagacc aacaatgagc tgactggcgc cctgcaccat ctaaggtgcg
     2401 ccagaataag atactatgtc aggtgtgtcc aggaggccct gtattccatc attcagattg
     2461 ctggggctgc atttgtcacc acgcgcatcg tcaagcgcat gaacatacaa gacctatggt
     2521 ccaagccaca agtggaaaac acagaggaga ctaccggcaa ggacgggtgt ccaagaccca
     2581 aagatgatga ggagttcgtc atttcatccg acgacatcaa aactgagggt aagaaaggga
     2641 agaacaagac tggccgcggc aagaagcaca cagccttctc aagcaaaggt ctcagtgatg
     2701 aagagtacga tgagtacaag aggattagag aggaaaggaa tggcaagtac tccatagaag
     2761 agtaccttca ggacagggac aaatactatg aggaggtggc cattgccagg gcgactgagg
     2821 aggacttctg tgaggaggag gaggccaaga tccggcagag gatcttcagg ccaacaagga
     2881 aacaacgcaa ggaggaaaga gcttctctcg gtttagttac aggttctgaa attaggaaaa
     2941 gaaatccaga tgatttcaaa cccaaaggga aactgtgggc tgacgatgac agaagtgtgg
     3001 actacaatga gaaactcagt tttgaagccc caccaagcat ctggtcgagg atagtcaact
     3061 ttggttcagg ttggggattc tgggtctccc ccagtctgtt cataacatca acccacgtca
     3121 taccccaggg cgcaaaggag ttctttggag tccccatcaa acaaattcag gtacataagt
     3181 caggcgaatt ctgtcgcttg agattcccaa aaccaatcag gactgatgtg acgggcatga
     3241 tcttagaaga aggtgcaccc gagggcaccg tggtcacact actcatcaaa aggtccactg
     3301 gagaactcat gcccctagca gctaggatgg ggacccatgc aaccatgaaa atccaaggac
     3361 gcactgttgg aggtcaaatg ggcatgcttc tgacaggatc caacgccaaa agcatggacc
     3421 tgggtaccac accaggtgat tgtggctgtc cctacatcta caagagagga aatgactatg
     3481 tggtcattgg agtccacacg gctgccgctc gtgggggaaa cactgtcata tgtgccaccc
     3541 aggggagtga gggagaggct acacttgaag gtggtgacaa taaagggaca tactgtggtg
     3601 caccaatcct aggcccaggg agtgccccaa aacttagcac caagaccaag ttttggagat
     3661 cgtccacagc atcactccca cctggcacct atgaaccagc ctatcttggt ggcaaggacc
     3721 ccagagtcaa gggtggccct tcactgcagc aagtcatgag ggatcagttg aagccattta
     3781 cagagcccag gggcaagcca ccaaagccaa gtgtgttgga agctgccaag aaaaccatca
     3841 tcaatgtcct tgagcaaaca attgatccac ctgagaaatg gtcattcgca caagcttgcg
     3901 cgtcccttga caagaccact tccagtggcc atccgcatca catgcggaaa aacgactgct
     3961 ggaacgggga gtccttcaca ggcaagctgg cagaccaggc ttccaaggcc aacctgatgt
     4021 ttgaagaagg gaagaacatg accccagtct acacagctgc gcttaaggat gaattagtta
     4081 aaactgacaa aatttatggt aagatcaaga agaggcttct ctggggctcg gatttggcga
     4141 ccatgattcg gtgtgctcga gcattcggag gcctaatgga tgaactcaaa gcgcactgtg
     4201 tcacacttcc cattagagtt ggtatgaata tgaatgagga tggccccatt atcttcgaga
     4261 ggcattccag gtacacatac cactatgatg ctgattactc tcgatgggat tcaacacaac
     4321 agagagccgt gttggcagca gctttagaaa tcatggttaa attttcccca gaaccacatt
     4381 tggctcaggt agtcgcagaa gaccttcttt ctcctagcgt ggtggacgtg ggtgacttca
     4441 caatatcaat caacgagggt cttccctctg gggtgccctg cacctcccaa tggaactcca
     4501 tcgctcactg gcttctcact ctctgtgcgc tctctgaagt tacaaacttg tctcctgaca
     4561 ccatacaggc taattccctc ttctcttttt atggtgatga tgaaattgtt agcacagaca
     4621 taaaattgga cccagagaag ttgacagcaa agctcaggga atatgggtta aagccaaccc
     4681 gccctgacaa aactgaagga ccccttgtca tctctgaaga cttgaatggc ctgactttcc
     4741 tgcggagaac tgtgacccgc gacccagctg gttggtttgg aaaattggag cagagttcaa
     4801 tactcaggca aatgtactgg actaggggtt ccaaccatga agacccatct gaaacaatga
     4861 tcccacactc ccaaagaccc atacaattga tgtccctact gggggaggcc gcactccacg
     4921 gcccagcatt ctacagcaaa atcagcaagt tagtcattgc agagctaaaa gaaggtggca
     4981 tggattttta cgtgcccaga caagagccaa tgttcagatg gatgagattc tcagatctga
     5041 gcacgtggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat
     5101 gacgccaccc catctgatgg gtccacagcc aacctcgtcc cagaggtcaa caatgaggtt
     5161 atggctttgg agcccgttgt tggtgccgcg attgcggcac ctgtagcggg ccaacaaaat
     5221 gtaattgacc cctggattag aaataatttt gtacaagccc ctggtggaga gtttacagta
     5281 tcccctagaa acgctccagg tgaaatatta tggagcgcgc ccttgggccc tgatttgaac
     5341 ccctaccttt cccatttggc cagaatgtac aatggttatg caggtggttt tgaagtgcaa
     5401 gtaatcctcg cggggaacgc gttcaccgcc gggaaaatca tatttgcagc agtcccacca
     5461 aatttcccaa ctgaaggctt gagccccagc caggtcacta tgttccccca tataatagta
     5521 gatgttaggc aactggaacc tgtgttgatc cccctgcctg atgttaggaa taatttctat
     5581 cattacaatc aatcaaatga ccccaccatc aaattgatag caatgctgta tacaccactt
     5641 agggctaaca atgctgggga cgatgtcttc acagtctctt gtcgagttct cacgagacca
     5701 tcccccgatt ttgatttcat atttttggtg ccacccacag ttgagtcaag aactaaacca
     5761 ttctctgtcc caatcttaac tgttgaggag atgaccaatt caaggttccc tattcctttg
     5821 gaaaagttgt tcacgggtcc cagcagtgcc tttgttgttc aaccacaaaa tggcagatgc
     5881 acgactgatg gcgtgctttt aggtactacc caactgtctc ctgtcaacat ctgcaccttc
     5941 agaggggatg tcacccacat tgcaggtact caaaattaca caatgaatct ggcctcccaa
     6001 aattggaaca attatgaccc aacagaagaa atcccagctc ctctgggaac cccagatttt
     6061 gtaggaagga tccaaggcgt gctcacccaa accacaagga gggacggctc gacccgcggt
     6121 cacaaagcca cagtaagcac tggaagtgtc cacttcaccc caaagctggg cagtgttcaa
     6181 ttctctactg atacaagcaa tgactttgaa actggccaaa acacgagatt caccccagtc
     6241 ggtgtcgtcc aggatggtag taccacccac caaaatgaac cccaacaatg ggtgctccca
     6301 gactattcag gtagagatag ccacaatgta cacctagccc ctgccgtggc ccccactttt
     6361 ccgggtgagc aacttctttt ctttaggtcc actatgcccg gatgcagcgg gtatcccaac
     6421 atgaatttgg attgcctact cccccaggag tgggtgcagc acttctacca agagtcagcc
     6481 ccagcacaat ctgatgtggc actgctgaga tttgtgaatc cagacacagg tagggttttg
     6541 tttgagtgca agcttcataa atcaggctat gtaacagtgg ctcacactgg ccaacatgat
     6601 ttggttatcc cccccaatgg ctattttaga tttgattcct gggtcaacca attctacaca
     6661 cttgccccca tgggaaatgg agcggggcgt agacgtgcat tataatggct ggagctttct
     6721 ttgctggatt ggcatctgat gtccttggct ctggacttgg ctctctaatc aatgctgggg
     6781 ctggggccat caaccaaaaa gttgagtttg aaaataacag aaaattgcaa caagcttcct
     6841 tccaatttag cagcaaccta caacaggctt cctttcaaca tgataaagag atgctccaag
     6901 cacaaattga ggccaccaaa aagttgcaac aggaaatgat gaaagttaaa caggcaatgc
     6961 tcctagaggg tgggttctct gagacagatg cagcccgtgg ggcagtcaac gcccccatga
     7021 caaaggcttt ggactggagc ggaacaaggt actgggctcc cgatgctagg actacaacat
     7081 acaatgcagg ccgcttttcc acccctcaac cctcgggggc atcgtcagga agaactaatc
     7141 ttagggctac tgtccccgct cggggctcct ccagcacacc ctctaatgct tctactgcta
     7201 cttctgtgta ctcaaatcaa actgcttcaa cgagacttgg ttctacagct ggttctggta
     7261 ccagtgtctc gagcctcccg tcaactgcaa ggactaggag ctgggttgag gatcaaaaca
     7321 ggaatttgtc acctttcatg aggggggccc acaacatatc gtttgtcacc ccaccatcta
     7381 gtagatcctc tagccaaggc acagtctcaa ccgtgcctaa agaagttttg gactcctgga
     7441 ctggcgcttt caacacgcgc aggcagcctc tcttcgctca cattcgtaag cgaggggagt
     7501 cacgggtgta atgtgaaaag acagaaattg attatcattc ttttcttcag tgtctttt
//