Typing tool

Complete norovirus genomes

MH218725  GI.3
 GI.P3

Length: 7,745 | 3 CDS

ORF1: 5..5404
ORF2: 5388..7025
ORF3: 7025..7672
LOCUS       MH218725                7745 bp    RNA     linear   VRL 11-JUN-2018
DEFINITION  Norovirus GI isolate NORO_84_04_11_2014, complete genome.
ACCESSION   MH218725
VERSION     MH218725.1
KEYWORDS    .
SOURCE      Norovirus GI
  ORGANISM  Norovirus GI
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus.
REFERENCE   1  (bases 1 to 7745)
  AUTHORS   Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
            Hartley,J., Harris,K. and Breuer,J.
  TITLE     Norovirus transmission dynamics in a paediatric hospital using full
            genome sequences
  JOURNAL   Clin. Infect. Dis. (2018) In press
   PUBMED   29800111
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7745)
  AUTHORS   Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
            Hartley,J., Harris,K. and Breuer,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-APR-2018) Division of Infection and Immunity,
            University College London, 90 Gower St, London, London WC1E 6BT,
            United Kingdom
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: CLC Genomics Workbench v. 10.1
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..7745
                     /organism="Norovirus GI"
                     /mol_type="genomic RNA"
                     /isolate="NORO_84_04_11_2014"
                     /host="Homo sapiens"
                     /db_xref="taxon:122928"
                     /country="United Kingdom"
                     /collection_date="04-Nov-2014"
                     /note="genotype: GI.P3_GI.3"
     gene            5..5404
                     /gene="ORF1"
     CDS             5..5404
                     /gene="ORF1"
                     /codon_start=1
                     /product="nonstructural polyprotein"
                     /protein_id="AWR17833.1"
                     /translation="MMMASNDAIAVADVSNNNANTNNDNIGSRLMARIRGRMGPQRGE
                     TTTKITDANMALNLLRRSQTPSPSRQESPPKSQRDRPPRTASEVKKVLGWDVEPEHQE
                     STAKAWCDLTQEEKEEIMRNNEKLFDAGGITPSTLPSTFERADPVDSPIEQQPVTWSA
                     SGGVDIGVNDLTTVSGPFWNMCPLPPLDARNNGPAKEPLIGDMIEFYEGHIFHYAIYI
                     GQGKTIGVHSPQAAFSIPRITIHPLVAWWRVCYVPTNQQRLTYDQLKELENEPWPYAS
                     ITNNCYEFCCRVMALDDTWLERRLVSTGKFNHPTQDWSQDTPDFHQDSKLEMVRDAVL
                     SAINGLVSQPFKNILSKIKPLNVLNLLSNCDWTFMGVVELIVLLAELFDVFWTPPDIS
                     SFIASLLPEFHLQGPEDLARDLVPLILGGIGLAIGFTRDKVTKVMKSAVDGLRSATQL
                     GQYGLEIFSIIKKYFFGGDQTEKTLRGIEDAVIDMEVLSSTNVTQLVKDKKLARTYMN
                     VLDNEEEKARKLSVRSADPHIVTSVNNLISRISMARSALAKAQAEMTSRPRPVVIMMC
                     GPPGIGKTKAAEHLAGRLANEIRPGGKVGLVPRESIDHWDGYHGEDVLLWDDYGMSKI
                     TEDCNKLQAIADTAPLSLNCDRIENKGMQFSSDAIIITTNAPGPAPVDFVNLGPVCRR
                     VDFLVYCSAPEIEQMRRTHPGDANAIKDLYKRDYSHLKMELAPQGGFDSQGNTPFGKG
                     IMKPTTLNRLLIQATALAMERQDEFQLQGAVYNFDEDRVSAFTSLARANGLGLLSMAT
                     LGKRLRSVKSMEGLRNALVGYKIGECDIIWNTRVYSIKSDGSTVTIKEKQTPTSPQYQ
                     AISTATLALSRLRAARALAYASCLQSAVLSILQVAGSALVVSRAVKRMFGTRTEQPML
                     EGKHKEHNCRVHRAEAAGHGPIGHDGVIERYGLCESEQEEEGEQTVELPTANKEGKNK
                     GKTKKGRGRKSNFNAFSRRGLSDEEYEEYKKIREEKSGNYSIQEYLEDRQRYEEELAE
                     VQAGGDGGIGETEAEIRHRVFYKSKSGMRKQRQEERRQLGLVSGSEIRKRKPIDWTPP
                     KNDWSEDTRTVNYDEHISFEAPPSIWSRVVKFGSGWGFWVSSTVFITTTHVIPPGAKE
                     VFGEDLSNVAIHRVGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCTIMIKRDSGELLP
                     LAVRMGAVASMKIQGKLMHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDWVVC
                     GVHAAATKSGNTVVCAIQGGDGEATLEGGGQNKGHYAGHPILRYGNGPSLSTKTKFWK
                     STPQPLPPGTYEPAYLGGRDPRVEGGPSLQQVLRDQLKPFAEPRGRLPEAGLLEAAVE
                     TVTNAIEQVMDTPVAWSYSDACMSLDKTTSSGHPHHKKKNDDWNGNSFVRELGDQAAH
                     ANSMYELGKSMKPVYTAALKDELVKPDKVYTKIKKRLLWGADLGTVIRAARAFGPFCE
                     AIKPHVIKLPIKVGMNAIEDGPLIYAEHSKYKFHYDADYTAWDSTQNREIMMESFNIM
                     CKLTANPSLAAVVAQDLLSPSEMDVGDYVISVKDGLPSGFPCTSQVNSINHWILTLCA
                     LSEVTGLSPDVIQSQSYFSFYGDDEIVSTDIEFDPIRLTQILKEYGLKPTRPDKTDGP
                     IIIRQQVDGLVFLRRTISKDAIGYQGRLDRNSIERQLWWTRGPNHEDPFETLVPHSQR
                     KVQLISLLGEAALHGEKFYRKIAGRVIQEVKEGGLEIYIPGWQAMFRWMRFHDLSLWT
                     GDRDLLPDYVNDDGV"
     mat_peptide     5..1219
                     /gene="ORF1"
                     /product="p48"
     mat_peptide     1220..2308
                     /gene="ORF1"
                     /product="NTPase"
     mat_peptide     2309..2908
                     /gene="ORF1"
                     /product="p22"
     mat_peptide     2909..3328
                     /gene="ORF1"
                     /product="VPg"
     mat_peptide     3329..3871
                     /gene="ORF1"
                     /product="Pro"
     mat_peptide     3872..5401
                     /gene="ORF1"
                     /product="RdRp"
     gene            5388..7025
                     /gene="ORF2"
     CDS             5388..7025
                     /gene="ORF2"
                     /codon_start=1
                     /product="VP1"
                     /protein_id="AWR17834.1"
                     /translation="MMMASKDAPTNMDGTSGAGQLVPEANTAEPISMEPVAGAATAAA
                     TAGQVNMIDPWIMNNYVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLSHLAQMYNG
                     WVGNMKVKVLLAGNAFTAGKIIISCIPPGFAAQNISIAQATMFPHVIADVRVLEPIEV
                     PLEDVRNVLFHNNDNTPTMRLVCMLYTPLRASGSSSGTDPFVIAGRVLTCPSPDFSFL
                     FLVPPNVEQKTKPFSVPNLPLNTLSNSRVPSLIKSMMVSRDHGQMVQFQNGRVTLDGQ
                     LQGTTPTSASQLCKIRGSVFHANGGNGYNLTELDGSPYHAFESPAPIGFPDLGECDWH
                     MEASPTTQFNTGDVIKQINVKQESAFAPHLGTVQVDGLSDVSVNTNMIAKLGWVSPVS
                     DGHKGDVDPWVIPRYGSTLTEAAQLAPPIYPPGFGEAIVFFMSDFPIAHGTNGLSVPC
                     TIPQEFVTHFVNEQAPTRGEAALLHYLDPDTNRNLGEFKLYPDGFMTCVPNSSGTGPQ
                     TLPINGVFVFVSWVSRFYQLKPVGTAGPARRLGIRRS"
     gene            7025..7672
                     /gene="ORF3"
     CDS             7025..7672
                     /gene="ORF3"
                     /codon_start=1
                     /product="VP2"
                     /protein_id="AWR17835.1"
                     /translation="MAQAILGAIAATAAGSAVGAGIQAGTEAALQHQRFQQDLTLQKN
                     SFIHDKEMMGLQVEASTALLQNSLGTRYNMLTKAGMTSADAARMVVGAPATRVVDWNG
                     TRIAAPMSTATTLRSGGFMTVPTVYRGSKNKQSIGGGFSNVNYDPSVSSSRTSQWVSS
                     QNLMRSTLEPFHPGALRTTWVTPPGSTSTSTISTVSTVPKFFNTERLPLFANRGK"
ORIGIN      
        1 gtgaatgatg atggcgtcta acgacgctat tgccgttgct gatgtcagca ataacaatgc
       61 taacaccaac aatgataaca ttggatcccg cctcatggcg aggatccgtg ggcgcatggg
      121 cccacaacgt ggtgaaacaa ccacaaaaat aacagacgcc aatatggcgc ttaatctgct
      181 acgccggtca caaacacctt ccccatcccg gcaagagagc cctcctaaga gccagagaga
      241 ccgaccccct cggactgctt ctgaggtgaa gaaagtgttg gggtgggatg ttgaaccaga
      301 acaccaggaa agcacggcca aggcatggtg cgacctcacg caagaagaga aggaggagat
      361 aatgcgcaat aatgaaaagc tcttcgatgc tgggggaatc accccatcaa ctttgcctag
      421 cacgtttgaa agggccgacc cagttgatag ccccattgaa cagcaacctg tgacatggtc
      481 tgctagtggt ggggtcgata ttggtgtcaa tgatttgacc accgtcagtg gcccattttg
      541 gaatatgtgc cccctcccgc cactggatgc tcggaataat ggccccgcta aggagcccct
      601 cataggagat atgatagagt tctatgaggg tcatatattc cattatgcca tctatattgg
      661 acaaggtaag accattgggg tccactcacc gcaagcagct ttctccatac caaggataac
      721 catccatcct ctggtagcct ggtggcgcgt gtgctacgtt ccaactaacc agcagcgcct
      781 cacttatgac cagctcaaag agttggagaa tgagccatgg ccctacgctt ccattacaaa
      841 caattgctat gagttttgct gcagagtgat ggcacttgac gacacatggc ttgagaggag
      901 gttagtcagc actggaaaat tcaatcaccc cacacaagat tggtcacagg ataccccgga
      961 ttttcaccag gactcgaaac ttgagatggt aagagatgcc gtgctatcag ctattaatgg
     1021 ccttgtgtca cagcccttta aaaacatttt gtcaaagatc aaaccattaa acgttctcaa
     1081 tctcttgtca aattgtgatt ggaccttcat gggggttgtg gaactgattg tgctcctagc
     1141 ggagttgttt gatgtgttct ggaccccacc agacatctca agtttcattg cctcactact
     1201 acctgaattt cacctgcagg gcccagaaga cctagctagg gacttggtcc ctctcatcct
     1261 aggtggcata ggcctggcta ttggctttac aagagacaaa gtgacgaaag tgatgaagag
     1321 tgccgtcgat gggttgagat cggcgacaca gctcgggcag tacggactgg aaatattctc
     1381 aatcatcaag aaatatttct ttggtgggga tcaaacggaa aagaccttgc ggggtattga
     1441 ggatgcagtg atagacatgg aggtgttatc tagcaccaat gtgacacaat tggttaaaga
     1501 taagaaattg gccagaacct acatgaatgt gctagacaat gaagaggaaa aagcaaggaa
     1561 actttcagtc cgtagtgctg atccgcacat agtgacctca gtcaacaatc tgatatcacg
     1621 aatatctatg gcaagatcag ccttggccaa agcccaggct gagatgacat ctcgcccacg
     1681 ccctgtggtc ataatgatgt gtggcccccc cggcatcgga aaaaccaagg ccgccgaaca
     1741 cctggctggc cgattggcaa acgagattag accaggaggt aaggttggac ttgtgccccg
     1801 ggaatccata gatcactggg acggatacca tggcgaggat gtcctactat gggatgacta
     1861 tggcatgtca aagataacag aggactgtaa taagctacaa gccatagctg acactgcacc
     1921 cctatcactt aattgtgaca ggatagagaa caaaggcatg caattctcct cagatgcaat
     1981 aatcataacc accaatgccc ctggcccggc cccggtggac tttgttaacc taggccctgt
     2041 gtgcaggcga gtagactttt tagtttactg ttctgcccct gaaattgagc aaatgagaag
     2101 gacccaccct ggtgatgcca atgccatcaa agacctatac aaaagggact actcacactt
     2161 aaaaatggaa ttggccccac aaggtggttt tgatagtcag ggtaacacac catttgggaa
     2221 gggcatcatg aaacccacga ccctcaatag gctactcatt caggcaacag cattagctat
     2281 ggagcggcaa gacgagttcc agctccaagg ggctgtctac aactttgatg aagacagggt
     2341 gtccgccttc acaagcctgg cccgagctaa cggcttgggg cttttaagca tggcaacatt
     2401 gggtaaaagg ctcagaagtg tcaaatctat ggagggcctg cgtaacgcat tggtgggcta
     2461 caaaatagga gagtgtgata taatctggaa cactagagtg tattcaatta aaagtgatgg
     2521 tagtactgtc acaatcaagg aaaaacaaac cccaacttca ccccaatacc aagccattag
     2581 cacagccact cttgcactct ctaggttgcg ggccgctaga gctctcgcgt acgcctcctg
     2641 cctgcagagt gcagtgctgt caatacttca agtagctggc tctgccctgg tggtgagcag
     2701 agccgttaag cgcatgtttg gcacgcgcac tgaacaacct atgttggaag gcaagcacaa
     2761 agaacacaac tgtagagtgc accgcgcaga ggcagctggc catggtccta ttgggcacga
     2821 tggagtcatc gaacgctatg gcctctgtga gagtgagcaa gaagaagaag gcgagcaaac
     2881 agttgagcta cccactgcca ataaagaagg caaaaacaag ggcaagacca aaaagggccg
     2941 tggacgaaaa tccaatttta atgctttctc aagacgaggc ctcagtgatg aagagtatga
     3001 agaatacaag aagatcagag aagaaaagag tggcaattac agcatccagg agtacctcga
     3061 ggaccgccaa cgatatgagg aagaacttgc tgaagtgcag gctggtgggg atggtggaat
     3121 tggtgagact gaagcagaga ttcgccatcg ggttttctat aaatcaaaat ccggcatgag
     3181 aaagcaacgc caagaagaac ggcgtcagtt gggtctcgtt agcggttctg agatccgcaa
     3241 acgcaagccc atagactgga ccccccctaa gaatgattgg tcagaagaca ccaggactgt
     3301 caactatgat gaacacatta gctttgaagc ccctccctca atttggagta gggtggtgaa
     3361 gtttggcagt ggttggggtt tttgggtgag ctcaacagta ttcataacca cgacccatgt
     3421 cataccacct ggggccaaag aagtctttgg tgaagacctc agtaatgtgg ccatccatag
     3481 agttggtgag ttcacccagt tccgtttctc caaaaagatg agacctgacc tcaccggtat
     3541 ggttttagaa gaaggttgcc cagagggaac agtgtgcacc ataatgatca agagagattc
     3601 tggtgagttg ctgccgctcg ctgttcggat gggggcagtg gcatcaatga agatccaagg
     3661 caaacttatg catgggcaat caggaatgtt actcaccggt gctaatgcca aaggcatgga
     3721 ccttgggact atacccggtg attgtggggc accctatgtc cacaagaggg gaaatgactg
     3781 ggtggtctgt ggagtgcatg cagccgccac aaaatcaggc aacactgtgg tgtgcgccat
     3841 acaaggtggc gatggtgaag ccactctaga aggcggcggt caaaacaagg gccactatgc
     3901 agggcatccg atactaaggt atgggaatgg cccttcacta tcaaccaaaa caaaattttg
     3961 gaaatcaacc ccccagcctt tgcctcctgg tacatatgag ccagcttacc ttggaggtag
     4021 agaccccaga gttgaggggg gcccatcctt acagcaggtg ttaagggacc agttgaaacc
     4081 atttgccgaa ccccgtggca gattacccga agcgggctta ttggaagctg cagttgaaac
     4141 ggtcaccaat gctattgaac aggtcatgga cacaccggtg gcatggagct atagtgatgc
     4201 ttgcatgtca ctagataaga caaccagttc cggccacccc catcacaaga agaaaaatga
     4261 tgattggaat gggaattcat ttgtgagaga attgggtgac caggcggcac acgctaacag
     4321 catgtatgag cttggtaagt ccatgaaacc tgtgtataca gcagccctaa aggatgagct
     4381 agtcaaacca gataaggtgt acacaaaaat caaaaagaga ctgctttggg gcgcggacct
     4441 cggtaccgtc attcgcgctg ccagagcatt tggaccattc tgtgaggcca taaaacccca
     4501 tgtaattaag ttgcctatca aggtgggtat gaatgccata gaggatggcc ccttgattta
     4561 tgctgagcac tccaaatata aatttcatta tgatgctgac tatacagctt gggactcaac
     4621 acaaaacagg gaaatcatga tggagtcttt caatattatg tgcaagctta cagccaatcc
     4681 ctccttggcc gcagtggtgg cacaggatct actctcccca tctgaaatgg atgttggtga
     4741 ctatgtaatc agtgtcaaag atggtttacc atctggcttt ccatgcactt cacaggtgaa
     4801 cagtatcaac cactggatac taaccctgtg tgcactgtca gaagtcactg gcttgtcccc
     4861 agatgtgata cagtcacaat cctacttctc attttatggt gatgatgaaa tagtctcaac
     4921 agatatagaa tttgacccaa ttagattgac acaaatactg aaggaatatg gtttgaagcc
     4981 tacaagacct gacaaaactg atggcccaat tattattaga caacaggttg atggcctggt
     5041 cttcctccgg cgcaccattt ctaaggatgc cattggatac cagggacgac tcgaccgtaa
     5101 ctctattgaa aggcagcttt ggtggactcg tggaccaaac catgaggacc catttgagac
     5161 actggtccca cattcacaga gaaaggtcca attaatatcc ttgctaggtg aagcagcact
     5221 ccacggtgaa aagttctaca ggaagatagc tggtagggtc attcaagaag tcaaagaggg
     5281 agggcttgaa atctacattc ctggttggca ggccatgttc cgctggatgc ggttccatga
     5341 tctaagtttg tggacaggag accgcgatct cctgcccgat tatgtaaatg atgatggcgt
     5401 ctaaggacgc cccaacaaac atggatggca ccagtggtgc cggccagctg gtaccagagg
     5461 caaacacagc tgagcctata tcaatggagc ccgtggctgg ggcagcaaca gctgccgcaa
     5521 ctgctggcca agttaatatg attgacccct ggataatgaa caattatgta caagcccccc
     5581 aaggtgaatt taccatatcg cctaataaca caccaggtga tattttgttt gatttacaat
     5641 taggccccca ccttaaccct ttcttatctc atttggccca aatgtataat ggctgggttg
     5701 gcaatatgaa agtgaaggtt ttattggctg gtaatgcttt cacggctggt aaaataatta
     5761 ttagttgcat acctcctggc tttgccgcac aaaatatttc tattgcccag gccaccatgt
     5821 tcccccatgt catagctgat gttagggttt tggaacccat tgaggtgcca ttggaagatg
     5881 tgaggaatgt gctcttccac aacaatgaca acacgccaac tatgcggttg gtgtgcatgc
     5941 tatacacccc cttgcgggcc agtggtagct cgtctggaac tgaccccttt gtgattgctg
     6001 ggcgtgtttt gacatgccca agtcctgatt ttagcttttt gtttttggtc ccccccaatg
     6061 tagagcaaaa gactaaacct ttcagtgtcc caaaccttcc attgaatact ctttcaaatt
     6121 cgagagtccc ttctttaatc aaatcaatga tggtgtccag ggaccatggg cagatggttc
     6181 agtttcaaaa tggtagggtc accctagatg ggcagctgca aggcaccaca cccacatcag
     6241 ctagtcagct gtgcaaaatc aggggcagtg tcttccatgc caatggtggg aatgggtaca
     6301 acttaacaga actggatggg agcccatacc acgcatttga aagccccgca ccaataggtt
     6361 ttccagatct aggtgaatgt gattggcaca tggaggcttc tcctaccacc caatttaaca
     6421 ctggagatgt tataaaacaa attaatgtta aacaagagtc agcatttgcc ccccaccttg
     6481 gcaccgtaca ggtagacggc ctgagtgatg tgagtgtcaa caccaacatg atagctaaat
     6541 taggatgggt gtctcccgtc agtgatggac acaaagggga tgtcgacccg tgggtcattc
     6601 cacgctatgg ttcaactctg actgaggccg cccaattagc ccccccaata tatcccccag
     6661 gctttggtga ggccattgtg tttttcatgt cagactttcc cattgcccat ggcaccaatg
     6721 gcttgagtgt gccttgcact ataccccaag aatttgtcac ccattttgtc aatgaacagg
     6781 cccctactag aggggaagca gccttgctac actatctgga ccctgatact aatagaaatc
     6841 ttggtgagtt taaattatac cctgatggct tcatgacatg tgtgcctaac tccagtggca
     6901 ctggtccaca aactcttcca atcaatggtg tctttgtctt tgtgtcctgg gtttctagat
     6961 tttatcaatt aaagcctgtg ggaacagccg gcccggctcg taggcttggg attaggagat
     7021 cataatggct caagccatac ttggagccat agcagcaaca gcagccggta gtgctgttgg
     7081 tgctggtata caagctggaa ccgaagctgc cctacagcat caaagatttc agcaagatct
     7141 gaccttacaa aagaattcct ttattcatga taaagagatg atgggcctac aggtagaggc
     7201 ttcaactgca ctcctccaaa acagcttggg tacgaggtac aatatgttga ccaaagcagg
     7261 gatgacatcc gcagacgcgg cacgtatggt agtgggggca cccgcgactc gtgtcgttga
     7321 ctggaacggg actaggatcg ccgcacccat gtcaactgcg acgacactta ggtctggcgg
     7381 tttcatgacc gtaccaactg tttatagggg tagtaagaat aaacaatcaa ttggtggtgg
     7441 tttttctaat gtaaattatg atccctcagt ctcctcttcc cgcacttctc aatgggtctc
     7501 ttctcaaaat ttaatgcgtt ccactctgga accgtttcat ccaggtgctc tgagaaccac
     7561 atgggtcacc ccacctgggt caacttctac ttctacaatt tctacagttt ctactgtgcc
     7621 aaaattcttt aatacagaaa ggttaccctt attcgcaaac aggggtaagt gattttgtaa
     7681 tatgaattag tgggcatcat attcaatttg gaatcaatta gatatttaga ttggcagatg
     7741 atgtt
//