Typing tool

Complete norovirus genomes

KC631815  GII.4 Yerseke
 GII.P4 Yerseke

Length: 7,507 | 3 CDS

ORF1: 4..5097
ORF2: 5078..6700
ORF3: 6700..7506
LOCUS       KC631815                7507 bp    RNA     linear   VRL 15-AUG-2013
DEFINITION  Norovirus Hu/GII.4/MI002/2011/USA ORF-1, ORF-2, and ORF-3 genes,
            complete cds.
ACCESSION   KC631815
VERSION     KC631815.1
KEYWORDS    .
SOURCE      Norovirus Hu/GII.4/MI002/2011/USA
  ORGANISM  Norovirus Hu/GII.4/MI002/2011/USA
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus.
REFERENCE   1  (bases 1 to 7507)
  AUTHORS   Taube,S., Kolawole,A.O., Hohne,M., Wilkinson,J.E., Handley,S.A.,
            Perry,J.W., Thackray,L.B., Akkina,R. and Wobus,C.E.
  TITLE     A mouse model for human norovirus
  JOURNAL   MBio 4 (4), e00450-13 (2013)
   PUBMED   23860770
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7507)
  AUTHORS   Taube,S., Kolawole,A.O., Hoehne,M., Handley,S.A., Perry,J.W.,
            Thackray,L.B., Akkina,R. and Wobus,C.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2013) Microbiology and Immunology, University of
            Michigan Medical School, 1150 West Medical Center Dr., Ann Arbor,
            MI 48109-5620, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: 454 GS-FLX platform v. 2011
            Coverage              :: 99.12%
            Sequencing Technology :: 454
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..7507
                     /organism="Norovirus Hu/GII.4/MI002/2011/USA"
                     /mol_type="genomic RNA"
                     /strain="Hu/GII.4/MI002/2011/USA"
                     /host="Homo sapiens"
                     /db_xref="taxon:1354725"
                     /country="USA"
                     /collection_date="2006"
     CDS             4..5097
                     /note="nonstructural polyprotein"
                     /codon_start=1
                     /product="ORF-1"
                     /protein_id="AGQ46698.1"
                     /translation="MASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQ
                     PPPREIPQRPPRPPTPELVKNIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPEES
                     NTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLA
                     RVELAPLSLYWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDSWL
                     SRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGKLR
                     PLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLA
                     VELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKK
                     EEANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKS
                     ASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREMAK
                     RIAASLTGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPL
                     TLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAK
                     RDFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGRGVMKTLTTGSLIARASG
                     LLHERLDEFELQGPTLTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGRQLKDVRTMPE
                     LKQALKNISIKKCQIVYSGCTYILESDGKGNVKVDRVQSASVQTNNELTGALHHLRCA
                     RIRYYVKCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVENTEETTSEDGCPK
                     PKDNEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKY
                     SIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTG
                     SEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSL
                     FITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTV
                     VTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCG
                     CPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPG
                     SAPKLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPRG
                     KPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCWNG
                     ESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLAT
                     MIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDST
                     QQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQ
                     WNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLREY
                     GLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQGSILRQMYWTRGSNH
                     EDPSETMIPHSQRPVQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPM
                     FRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
     CDS             5078..6700
                     /note="VP1"
                     /codon_start=1
                     /product="ORF-2"
                     /protein_id="AGQ46696.1"
                     /translation="MKMASSDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
                     QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNSYAGG
                     FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
                     VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
                     TVESRTKPFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
                     QLSPVNICTFRGDVTHIAGTQEYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
                     TQTTRRDGSTRGHKATVSTGSVHFTPKLGRIQFSTDTSNDFETGQNTRFTPVGVVQDG
                     STTHQNEPQQWVLPNYSGRDSHNVHLAPAVAPSFPGEQLLFFRSTMPGCSGYPNMNLD
                     CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
                     IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
     CDS             6700..7506
                     /note="VP2"
                     /codon_start=1
                     /product="ORF-3"
                     /protein_id="AGQ46697.1"
                     /translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
                     SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMIKVKQAMLLEGGFSETDAARGAIS
                     APMTKTLDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNLRAAVPAWGSSSTPS
                     NSSTATSVYSNQTASTRLGSTAGSGTSVSSFPSTARTRSWVEDQNRNLSPFMRGAHNI
                     SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN      
        1 aagatggcgt ctaacgacgc ttccgctgcc gctgttgcta acagcaacaa cgacaccgca
       61 aaatcttcaa gtgacggagt gctttctagc atggctgtca cttttaaacg ggccctcggg
      121 gcgcggccta aacagcctcc cccgagggaa ataccacaaa gacccccacg accacctact
      181 ccagaactgg ttaaaaatat tccccctccc ccgcccaacg gagaggatga aatagtggtt
      241 tcttatagtg tcaaagatgg tgtttccggt ttacctgacc tttccaccgt caggcaaccg
      301 gaagaatcta acacggcctt cagtgtccct ccactcaatc agagggagaa tagagatgct
      361 aaggagccac tgactggaac aattctggaa atgtgggatg gagaaatcta ccattatggc
      421 ctgtatgtgg agcgaggtct tgtactaggt gtgcacaaac caccagctgc cattagcctc
      481 gctagggtcg agctagcacc actctccttg tactggagac ctgtgtacac tccccagtac
      541 ctcatctctc cagacactct caagaaatta cacggagaaa cgttccccta cacagccttt
      601 gataacaatt gttatgcctt ttgttgctgg gtcctggacc taaatgactc gtggctgagc
      661 aggagaatga tccagagaac aactggtttc ttcaggccct accaagattg gaataggaaa
      721 cccctcccca ctatggatga ctccaaatta aagaaggtag ctaacatatt cctgtgtgct
      781 ctgtcttcgc tattcaccag gcccataaaa gatataatag ggaagctaag gcctcttaac
      841 atcctcaaca tcttagcctc atgtgattgg acttttgcag gcatagtgga gtccctgata
      901 ctcttggcag aactctttgg agttttctgg acacccccag atgtgtctgc gatgattgcc
      961 cccttactcg gtgactacga gctacaagga cctgaggacc ttgcagtgga gctcgtcccc
     1021 gtagtgatgg ggggaattgg tttggtgcta ggattcacca aagagaagat tgggaaaatg
     1081 ttgtcatctg ctgcatccac cttaagagct tgtaaagacc ttggtgcata tgggctagag
     1141 atcctaaagt tggtcatgaa gtggttcttc ccgaagaagg aggaagcaaa tgaattggct
     1201 atagtgagat ctatcgagga tgcagtcctg gatctcgagg caattgaaaa caaccatatg
     1261 accaccttgc tcaaagacaa agacagtctg gcaacctata tgagaaccct tgaccttgag
     1321 gaggagaaag ccaggaaact ctcaaccaag tctgcctcac ctgacatcgt gggcacaatc
     1381 aacgcccttc tggcgagaat cgctgctgca cgctctctgg tgcatcgagc gaaggaggaa
     1441 ctttccagca gaccaagacc tgtagtattg atgatatcag gcagaccagg aatagggaag
     1501 acccaccttg ctagggaaat ggctaagaga atcgcagcct cccttacagg agaccagcgt
     1561 gtaggcctcg tcccacgcaa tggcgtcgac cactgggatg cgtacaaggg ggagagggtc
     1621 gtcctatggg acgattatgg gatgagcaat cccattcacg atgccctcag gttgcaagaa
     1681 ctcgctgaca cttgccccct cactctaaac tgtgacagga ttgagaacaa aggaaaggtc
     1741 tttgacagcg atgtcatcat tatcaccact aatctggcca acccagcacc actggactat
     1801 gtcaactttg aagcatgctc gaggcgcatc gacttcctcg tgtatgcaga agctcctgaa
     1861 gtcgaaaagg cgaagcgtga cttcccaggc caacctgaca tgtggaagaa cgccttcagt
     1921 tctgatttct cacacataaa actaacattg gccccacagg gtggcttcga caagaacggg
     1981 aacaccccac acggaagggg cgtcatgaag actctcacca ctggctccct tattgcccgg
     2041 gcatcaggac tactccatga gaggttagat gaatttgaac tacagggccc aactctcact
     2101 accttcaatt tcgatcgcaa taaagtgctt gcctttagac aacttgctgc tgaaaacaaa
     2161 tatgggttga tggacacaat gagagttggg agacagctca aggatgtcag aaccatgcca
     2221 gaactcaaac aagcactcaa gaacatttca atcaagaagt gccagatagt gtatagtggt
     2281 tgcacctata tacttgagtc tgatggcaag ggcaatgtga aagttgatag agttcagagc
     2341 gcctccgtgc agaccaacaa tgagctgact ggtgccctgc accatttgag gtgcgccagg
     2401 atcagatact atgtcaagtg tgtccaggag gccctgtatt ccatcatcca aattgctggg
     2461 gctgcgtttg tcaccacgcg catcgtcaag cgcatgaaca tacaagacct atggtccaag
     2521 ccacaagtgg aaaacacaga ggagaccacc agtgaggacg ggtgcccaaa acccaaagat
     2581 aatgaggagt ttgtcatttc atccgacgac atcaaaactg agggtaagaa agggaagaac
     2641 aagactggcc gcggcaagaa gcacacagcc ttttcaagca aaggtctcag tgatgaagag
     2701 tacgatgagt acaagaggat tagagaagaa aggaatggca agtactccat agaagagtac
     2761 cttcaggaca gggacaaata ctatgaggag gtggccattg ccagggcgac tgaggaagac
     2821 ttctgtgaag aggaggaggc caagatccgg caaaggatct tcaggccaac aaggaaacaa
     2881 cgcaaggagg aaagagcttc tctcggtctg gtcacaggtt ccgaaattag gaaaagaaac
     2941 ccagatgatt tcaaacccaa ggggaaactg tgggctgacg atgacagaag tgtggactat
     3001 aatgagaaac tcagctttga ggccccacca agcatctggt cgaggatagt taactttggt
     3061 tcaggttggg gattctgggt ctcccccagt ctgttcataa catcaaccca tgtcataccc
     3121 cagggcgcaa aggagttctt tggagtcccc atcaaacaaa ttcaggtaca caagtcaggc
     3181 gagttctgtc gcttgagatt cccaaaacca atcaggactg atgtgacagg catgatctta
     3241 gaagaaggcg cacccgaggg caccgtggtc acactactca tcaaaaggtc cactggggaa
     3301 ctcatgcccc tagcagctag gatggggacc catgcaacca tgaagatcca agggcgcacc
     3361 gttggaggcc aaatgggcat gcttctgaca ggatccaacg ccaaaagcat ggatctgggt
     3421 actacaccag gtgattgtgg ctgtccctac atctacaaga gaggaaatga ctatgtggtc
     3481 attggagtcc acacggctgc cgctcgtggg ggaaacactg tcatatgtgc cacccagggg
     3541 agtgagggag aggctacact tgaaggtggt gacaacaagg ggacatactg tggtgcacca
     3601 atcctaggcc cagggagtgc cccaaaactt agcaccaaga ccaaattctg gagatcgtcc
     3661 acggcatcac tcccacctgg cacctatgaa ccagcctatc ttggtggcaa ggaccctaga
     3721 gtcaagggtg gcccttcact gcagcaagtt atgagggaac agttgaagcc attcacagag
     3781 cccaggggca agccaccaaa gccaagtgtg ttagaagctg ccaagaagac catcatcaat
     3841 gtccttgagc aaacaattga tccacctgag aaatggtcat tcgcacaagc ttgcgcgtcc
     3901 cttgacaaga ccacttccag tggccatccg caccacatgc ggaaaaacga ctgctggaac
     3961 ggggagtcct tcacaggcaa gctagcagac caggcttcca aggccaatct gatgtttgaa
     4021 gaagggaaga acatgacccc agtctacaca gctgcgctca aggatgaatt agttaaaacc
     4081 gacaaaattt atggtaagat caagaagagg cttctctggg gctcggactt ggcgaccatg
     4141 atccggtgtg ctcgagcatt cggaggccta atggatgagc tcaaagcaca ctgtgtcaca
     4201 cttcccatta gagttggtat gaatatgaat gaggatggcc ccatcatctt cgagaggcat
     4261 tccaggtaca catatcacta tgatgctgat tactctcgat gggattcaac acaacagaga
     4321 gccgtgttgg cagcagctct agaaatcatg gttaaattct ccccagaacc acatttggct
     4381 caggtggtcg cggaagacct tctttctcct agcgtggtgg acgtgggcga cttcacaata
     4441 tcaatcaacg agggtcttcc ctctggggtg ccctgcacct cccaatggaa ctccatcgcc
     4501 cactggcttc tcactctttg tgcgctctct gaagttacaa acttgtcccc tgataccata
     4561 caggctaatt ccctcttctc tttttatggt gatgatgaaa ttgttagcac agacataaaa
     4621 ttggacccag agaaattgac agcaaagctc agggaatatg ggttaaaacc aacccgtcct
     4681 gacaaaactg aaggacccct tgtcatctct gaagacttga atggcctgac cttcctgcgg
     4741 agaactgtga cccgcgatcc agctggttgg tttggaaaac tggagcaggg ttcaatactc
     4801 aggcaaatgt actggactag gggctccaac catgaagacc catctgaaac aatgattcca
     4861 cactcccaaa gacccgtaca attgatgtcc ctactggggg aggccgctct tcacggccca
     4921 gcattctaca gcaaaatcag caagttagtc attgcagagc taaaagaagg tggcatggat
     4981 ttttacgtgc ccagacaaga gccaatgttc agatggatga gattctcaga tcttagcacg
     5041 tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt cgagtgacgc
     5101 caacccatct gatgggtcca cagccaacct cgtcccagag gtcaacaatg aggttatggc
     5161 tttggagccc gttgttggtg ccgctattgc ggcacctgta gcgggccaac aaaatgtaat
     5221 tgacccctgg attagaaata attttgtaca agcccctggt ggagagttta cagtatcccc
     5281 tagaaacgct ccaggtgaaa tactatggag cgcgcccttg ggccctgatt tgaatcccta
     5341 cctttcccat ttggccagaa tgtacaatag ttatgcaggt ggttttgaag tgcaggtaat
     5401 cctcgcgggg aacgcgttca ccgccggaaa aatcatattt gcagcagtcc caccaaattt
     5461 cccaactgaa ggcttgagcc ccagccaggt cactatgttc ccccatataa tagtagatgt
     5521 taggcaactg gaacctgtgt tgatcccctt acccgatgtt aggaataatt tctatcacta
     5581 caatcaatca aatgacccca ccatcaaatt gatagcaatg ttgtatacac cacttagggc
     5641 taataatgct ggggacgatg tcttcacagt ttcttgtcgg gttctcacga gaccatcccc
     5701 cgattttgat ttcatatttt tagtgccacc cacagttgag tcaagaacta aaccattctc
     5761 tgtcccaatt ttaactgttg aggagatgac caattcaaga ttccccattc ctttggaaaa
     5821 gttgttcacg ggtcccagca gtgcctttgt tgttcaacca caaaatggca ggtgcacgac
     5881 tgatggcgtg ctcctaggta ctacccaact gtctcctgtc aacatctgca ccttcagagg
     5941 ggatgtcacc cacattgcag gtactcaaga atacacaatg aatctggcct cccaaaactg
     6001 gaacaattat gatccaacag aagaaatccc agcccctctg ggaactccag atttcgtggg
     6061 taagatccaa ggcgtgctca cccaaaccac aaggagggat ggctcgaccc gcggtcacaa
     6121 agccacagtg agcactggaa gtgtccactt caccccaaag ctgggcagaa ttcaattctc
     6181 cactgataca agcaatgatt ttgaaactgg ccaaaacacg agattcaccc cagtcggtgt
     6241 tgtccaggat ggtagcacca cccaccaaaa tgaaccccaa caatgggtac tcccaaatta
     6301 ttcaggtaga gatagccaca atgtgcacct agcccctgct gtggccccct cttttccggg
     6361 tgagcaactt cttttcttca ggtccactat gcccggatgc agcgggtatc ccaacatgaa
     6421 tttggattgc ctactccccc aggagtgggt gcagcacttc taccaagagg cagccccagc
     6481 acaatctgat gtggctctgc taagatttgt gaatccagac acaggtaggg ttctgtttga
     6541 gtgtaagctt cataaatcag gctatgtcac agtggctcac actggccaac atgatttagt
     6601 tatccccccc aatggctatt ttaggtttga ttcctgggtc aaccagttct acacacttgc
     6661 ccccatggga aatggaacgg ggcgtagacg tgcattataa tggctggagc tttctttgct
     6721 ggattggcat ctgatgtcct tggctctgga cttggttccc taatcaatgc tggggctggg
     6781 gccatcaacc aaaaagttga atttgaaaat aacagaaaat tgcaacaagc ttccttccaa
     6841 tttagcagca acctacaaca ggcttccttt caacatgata aagagatgct ccaagcacaa
     6901 attgaggcca ccaaaaagtt gcaacaggaa atgataaaag ttaaacaggc aatgctccta
     6961 gagggtgggt tctctgagac agatgcagcc cgtggggcaa tcagcgcccc catgacaaag
     7021 actttggact ggagcgggac aaggtactgg gctcccgatg ctaggactac aacatacaat
     7081 gcaggccgct tttccacccc tcaaccctcg ggggcactgc caggaagaac taatcttagg
     7141 gctgctgtcc ccgcctgggg ctcctccagt acaccttcta actcttctac tgctacttct
     7201 gtgtactcaa atcaaactgc ttcaacgaga cttggttcta cagctggttc tggtaccagt
     7261 gtctcgagct tcccgtcaac tgcaaggact aggagctggg ttgaggatca aaataggaat
     7321 ttgtcacctt tcatgagggg ggcccacaac atatcgtttg tcaccccacc atctagcaga
     7381 tcctctagcc aaggcacagt ctcaaccgtg cctaaagaag ttttggactc ctggactggc
     7441 gctttcaaca cgcgcaggca gcctctcttc gctcacattc gtaagcgagg ggagtcacgg
     7501 gcgtaag
//