Typing tool

Complete norovirus genomes

AB541305  GII.4 Den Haag
 GII.P4 Den Haag

Length: 7,512 | 3 CDS

ORF1: 1..5103
ORF2: 5084..6706
ORF3: 6706..7512
LOCUS       AB541305                7512 bp    RNA     linear   VRL 03-AUG-2010
DEFINITION  Norovirus Hu/GII-4/Nagano3/2007/JP genomic RNA, complete genome.
ACCESSION   AB541305
VERSION     AB541305.1
KEYWORDS    .
SOURCE      Norovirus Hu/GII-4/Nagano3/2007/JP
  ORGANISM  Norovirus Hu/GII-4/Nagano3/2007/JP
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus.
REFERENCE   1
  AUTHORS   Motomura,K., Yokoyama,M., Ode,H., Nakamura,H., Mori,H., Kanda,T.,
            Oka,T., Katayama,K., Noda,M., Tanaka,T., Takeda,N. and Sato,H.
  CONSRTM   Norovirus Surveillance Group of Japan
  TITLE     Genome Recombination for Independent and Concurrent Evolution of
            Non-structural and Capsid Proteins of Norovirus GII/4 in Humans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7512)
  AUTHORS   Motomura,K. and Sato,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2010) Contact:Kazushi Motomura National Institute
            of Infectious Diseases, Center for Pathogen Genomics; Gakuen 4-7-1,
            Musashi-Murayama, Tokyo 208-0011, Japan
COMMENT     These sequences were determined at our laboratory.
FEATURES             Location/Qualifiers
     source          1..7512
                     /organism="Norovirus Hu/GII-4/Nagano3/2007/JP"
                     /mol_type="genomic RNA"
                     /strain="Hu/GII-4/Nagano3/2007/JP"
                     /isolation_source="stool"
                     /db_xref="taxon:707488"
                     /country="Japan:Nagano"
     CDS             1..5103
                     /note="contains N-terminal NTPase 3A VPg 3Cpro and 3Dpol"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="BAJ13845.1"
                     /translation="MKMASNDASAAAVANSNNDTAKSSSDKMFSSMAVTFKRALGARP
                     KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEDEVVVSYSAKDGVSGLPELSTVRQPE
                     ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
                     LAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
                     WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
                     LRPLNIINILASCDWTFAGIVESLILLAEFSLGVFWTPPDVSAMIAPLLGDFELQGPE
                     DLVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
                     PKKEEENELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLS
                     TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLARE
                     VAKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADT
                     CPLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVE
                     KAKRDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
                     ASGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKT
                     MPELKQALKNISIKKCQIVYNGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHL
                     RCARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATNKDG
                     CPKPKDIEEFVISSDDIKTEGKKGKNKAGRGKKHTAFSSKGLSDEEYDEYKRIREERN
                     GKYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGL
                     VTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVS
                     PSLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPE
                     GTVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
                     DCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPIL
                     GPGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTE
                     PRGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDC
                     WNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSD
                     LATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
                     DSTQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPC
                     TSQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKL
                     KEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRG
                     PNHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQ
                     EPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
     CDS             5084..6706
                     /codon_start=1
                     /product="VP1"
                     /protein_id="BAJ13846.1"
                     /translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
                     QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
                     FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
                     VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
                     TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
                     QLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
                     TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTENDFETHQNTKFTPVGVIQDG
                     GTTHRNEPQQWVLPSYSGRNVPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
                     CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
                     IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
     CDS             6706..7512
                     /codon_start=1
                     /product="VP2"
                     /protein_id="BAJ13847.1"
                     /translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
                     SFQFSSNLQQASFQHDKEMLQAQVEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
                     APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRINPRTSTPARGSPSTSS
                     NASTATSIYSNQTVSTRLGSTAGSGTNVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
                     SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRRRGESRV"
ORIGIN      
        1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacacc
       61 gcaaaatctt caagtgacaa aatgttttct agcatggctg tcacttttaa acgagccctc
      121 ggggcgcggc ctaaacagcc ccccccgagg gaaataccac aaagaccccc acgaccacct
      181 actccagaac tggtcaaaaa gatccctcct cccccgccca acggagagga tgaagtagtg
      241 gtttcttata gtgccaaaga tggcgtttcc ggtttacctg agctttccac cgtcaggcaa
      301 ccggaagaaa ccaacacggc cttcagtgtc cctccactca atcagaggga gaacagggat
      361 gctaaggagc cactgactgg aacaattctg gaaatgtggg atggagaaat ctaccattat
      421 ggcctgtatg ttgagcgagg tcttgtgctg ggtgtgcaca aaccaccagc tgccattagc
      481 ctcgccaagg tcgaactaac accactctcc ttgttctgga gacctgtgta cactcctcag
      541 tacctcatct ctccagacac tctcaagaaa ttacacggag aaacattccc ctacacagcc
      601 ttcgacaaca attgctatgc cttttgttgc tgggtcctgg atctaaacga ctcgtggctg
      661 agtaggagaa tgatccagag aacaactggc ttcttcagac cctaccaaga ttggaatagg
      721 aaacccctcc ccactatgga tgattccaaa ttaaagaagg tagctaatat attcctgtgc
      781 accctgtctt cgcttttcac caggcccata aaagacataa tagggaagtt aaggcctctc
      841 aacatcatca acatcctggc ttcatgtgat tggactttcg caggcatagt ggagtccttg
      901 atactcttgg cagagttctc tttgggagtc ttctggacac ccccagatgt gtctgcgatg
      961 attgccccct tactcggtga tttcgagtta caaggacctg aggaccttgt agtagagctc
     1021 gtccctgtag taatgggggg aattggtttg gtgctaggat tcaccaaaga gaagattgga
     1081 aaaatgttgt catctgctgc atctaccttg agagcttgta aagatcttgg tgcatatggg
     1141 ctagagatcc taaagttagt catgaagtgg ttcttcccga agaaagagga agaaaatgaa
     1201 ctggctatgg tgagatccat cgaggatgca gtactggacc ttgaggcaat tgaaaacaac
     1261 catatgacca ccttgctcaa agacaaagac agcctggcaa cctatatgag aacccttgac
     1321 ctcgaggaag agaaagccag aaaactctca accaagtctg cttcacctga catcgtgggc
     1381 acaatcaacg cccttctggc gagaatcgcc gctgcacgct ccctggtgca ccgagcgaag
     1441 gaggagcttt ccagcagacc aagacctgta gtcttgatga tatcaggcag accaggaata
     1501 gggaagaccc accttgctag ggaagtggct aagagaatcg cagcctccct cacaggagat
     1561 cagcgtgtgg gtctcatccc acgcaatggc gtcgatcact gggatgcgta caagggggag
     1621 agggtcgtcc tatgggacga ctatggaatg agcaatccca tccacgacgc cctcaggctg
     1681 caagaactcg ctgacacttg ccccctcact ctaaattgtg acaggattga gaataaagga
     1741 aaggtctttg acagcgatgt catcatcatc actactaacc tggccaaccc agcaccactg
     1801 gactatgtca actttgaagc gtgctcgagg cgcatcgatt tcctcgtgta tgcagaagcc
     1861 cccgaggtcg aaaaggcgaa gcgtgacttc ccgggccaac ctgacatgtg gaaaaacgct
     1921 tttagttctg atttctcaca cataaaattg gcactggctc cacaaggtgg ctttgataag
     1981 aacgggaaca ccccacacgg gaagggcgtc atgaagactc tcaccactgg ctccctcatt
     2041 gcccgggcat cagggctgct ccatgagaga ttggatgagt ttgaactaca gggcccagct
     2101 cttaccacct tcaactttga ccgcaacaaa gtgcttgcct tcaggcagct tgctgctgaa
     2161 aacaaatacg ggttgatgga cacaatgaaa gttgggaggc agctcaagga tgtcaaaacc
     2221 atgccagaac ttaaacaagc actcaagaat atctcaatca agaagtgcca gattgtgtat
     2281 aatggttgca cctacacact tgagtctgat ggtaagggca atgtgaaagt tgacagagtt
     2341 cagagcacct ccgttcagac caacaatgag ctggctggcg ccctgcacca tctaaggtgc
     2401 gccagaatca ggtactatgt caagtgtgtt caggaggccc tgtattctat catccagatt
     2461 gctggggctg catttgtcac cacgcgcatc atcaagcgtg tgaacattca agacttatgg
     2521 tccaagccac aagtggaaaa cacagaagag gctaccaaca aggacgggtg cccaaaaccc
     2581 aaagatattg aggagttcgt catttcatct gacgacatta aaaccgaggg taagaaaggg
     2641 aagaacaagg ctggccgtgg caagaagcac acagccttct caagtaaagg tctcagtgat
     2701 gaagagtatg atgagtacaa gagaattaga gaggagagga atggcaagta ctccatagaa
     2761 gagtacctac aggacaggga caaatactat gaggaggtgg ccattgccag ggcgaccgag
     2821 gaagacttct gtgaagagga ggaggccaag atccggcaaa ggatcttcag accaacaagg
     2881 aaacaacgca aggaagaaag agcttctctc ggtttagtca caggttctga aattaggaaa
     2941 aggaacccag aagacttcaa gcctaagggg aaactatggg ctgacgatga cagaagtgtg
     3001 gactacaatg aaaaactcag ctttgaggcc ccaccaagca tctggtcaag gatagtcaac
     3061 tttggctcag gttggggctt ctgggtctcc cccagcctgt tcataacatc aacccacgtc
     3121 ataccccagg gcgcaaagga gttctttgga gtccccatca aacaaattca ggtgcacaag
     3181 tcaggcgaat tctgtcgctt gaggttccca aaaccaatca ggactgatgt gactggcatg
     3241 atcttggaag aaggtgcgcc cgaaggcacc gtggtcacac tactcatcaa aaggtctact
     3301 ggagaactca tgcccctagc agctagaatg gggacccatg caaccatgaa gattcaaggg
     3361 cgcactgttg gaggtcagat gggcatgctt ctgacgggat ccaacgccaa aagcatggat
     3421 ctaggcacca caccaggtga ttgcggctgt ccctacatct acaagagagg aaacgactat
     3481 gtggtcattg gagtccacac ggctgccgct cgtgggggaa acactgtcat atgtgccacc
     3541 cagggaggtg agggggaagc tacacttgaa ggtggtgaca gtaagggaac atactgtggt
     3601 gcaccaatcc taggcccagg gagtgcccca aaacttagca ccaaaaccaa attctggagg
     3661 tcatccacag caccactccc acctggcacc tatgaaccag cctacctagg tggcaaggac
     3721 cccagggtca agggtggccc ctcgttgcag caagtcatga gggaccagct gaaaccattt
     3781 acagagccta ggggtaagcc accaaagcca agcgtgttag aagctgccaa gaaaaccatc
     3841 atcaatgtcc ttgaacaaac aattgaccca cctgagaagt ggtcgttcgc acaagcttgc
     3901 gcgtcccttg acaagaccac ttctagcggc catccgcacc acatgcggaa aaacgactgc
     3961 tggaacgggg aatccttcac aggcaagctg gcagaccagg cttccaaggc caacttgatg
     4021 tttgaagaag ggaagaacat gaccccagtc tacacaggtg cacttaagga tgaattagtc
     4081 aaaactgaca aaatttatgg taagatcaag aagaggcttc tctggggctc ggatttagca
     4141 accatgatcc ggtgtgctcg agcattcgga ggcctaatgg atgaactcaa agcacactgt
     4201 gtcacactcc ctatcagagt tggtatgaat atgaatgagg atggccccat catcttcgag
     4261 aagcattcca ggtacagata ccactatgat gctgattact ctcggtggga ttcaacacaa
     4321 cagagagccg tgctggcagc tgctctagaa atcatggtta aattctcctc agaaccacat
     4381 ttggctcagg tagtcgcaga agaccttctt tctcctagcg tggtggatgt gggtgacttc
     4441 acaatatcaa tcaacgaggg tcttccctct ggggtgccct gcacctccca atggaactcc
     4501 atcgcccact ggcttctcac tctctgtgca ctctccgaag ttacaaattt gtccccagac
     4561 atcatacagg ctaattctct cttctccttc tatggtgatg atgaaattgt tagtacagac
     4621 ataaaattag atccagagaa gttgacagca aagcttaagg aatacgggtt gaaaccaacc
     4681 cgccctgata aaactgaagg acctcttgtt atttctgaag acttagatgg tttgactttc
     4741 ctgcggagaa ctgtgacccg cgacccagct ggttggtttg gaaaattgga gcagagctca
     4801 atactcaggc aaatgtactg gactaggggc cccaaccatg aagatccatc tgaatcaatg
     4861 attccacact ctcaaagacc catacaattg atgtccttac tgggagaggc cgcactccac
     4921 ggcccaacat tctacagtaa aatcagcaaa ttagtcattg cagagctaaa agaaggtggt
     4981 atggattttt acgtgcccag gcaagagcca atgttcagat ggatgagatt ctcagatctg
     5041 agcacgtggg agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgaa
     5101 tgacgccaac ccatctgatg ggtccgcagc caacctcgtc ccagaggtca acaatgaggt
     5161 tatggctttg gagcccgttg tcggtgccgc tattgcggcg cctgtagcgg gccaacaaaa
     5221 tgtaattgac ccctggatta gaaataattt tgtacaagcc cctggtggag agttcacagt
     5281 atcccctaga aacgctccag gtgaaatact atggagcgcg cccttaggcc ctgatctgaa
     5341 tccctaccta tctcatttgg ccagaatgta taatggttat gcaggtggct ttgaagtgca
     5401 ggtgatcctc gcggggaacg cgttcaccgc cggaaaaatt atatttgcag cagtcccacc
     5461 aaattttcca actgaaggct tgagtcccag ccaggtcact atgttccccc acataatagt
     5521 ggatgttagg caattggaac ctgtgttgat ccccttacct gatgttagga ataacttcta
     5581 tcactataat cagtcaaatg attctaccat taaattgata gcaatgttgt atacaccact
     5641 tagggctaat aatgctgggg aagatgtctt tacagtctct tgtcgagttc tcacgaggcc
     5701 atcccctgat tttgatttta tatttttggt gccacctaca gttgagtcaa gaactaaacc
     5761 atttactgtc ccaatcttaa ctgttgaaga gatgaccaat tcaagattcc ccattccttt
     5821 ggaaaaattg ttcacgggtc ccagcagtgc ctttgttgtt caaccacaaa atggcagatg
     5881 cacgactgat ggcgtgctct taggcaccac ccaactgtct cctgtcaaca tctgcacctt
     5941 cagaggggat gtcacccaca ttgcaggttc tcgtaattac acaatgaatt tggcttctct
     6001 aaattggaac aattatgacc caacagaaga aattccagcc cctctaggaa ccccagattt
     6061 cgtgggaaag atccaaggag tgctcactca aaccacaaag ggagatggct cgacccgtgg
     6121 ccataaagct acagtttaca ctgggagtgc cccctttact ccaaagctgg gcagtgttca
     6181 attcagtact gatacagaaa atgattttga aactcaccaa aacacaaaat tcaccccagt
     6241 cggtgtcatc caggatggtg gcaccaccca ccgaaatgaa ccccaacaat gggtgctccc
     6301 aagttattca ggtagaaatg tccctaatgt acacctagcc cctgctgtag cccccacttt
     6361 tccgggtgaa caacttcttt tctttaggtc cactatgccc ggatgcagcg ggtatcccaa
     6421 catggatttg gattgcctgc tcccccagga gtgggtgcag cacttctacc aagaggcagc
     6481 tccagcacaa tctgatgtgg ctctattgag atttgtgaat ccagacacgg gtagggtcct
     6541 gtttgagtgc aagcttcaca aatcaggcta tgtcacagtg gctcacaccg gccagcatga
     6601 tttggtcatc ccccccaatg gttattttag gtttgattcc tgggttaatc agttctacac
     6661 acttgccccc atgggaaatg gaacggggcg tagacgtgct ttataatggc tggagctttc
     6721 tttgctggat tggcatctga tgtccttagc tctggacttg gttccctaat caatgctggg
     6781 gctggggcta tcaaccaaaa gattgatttt gaaaataaca gaaaattgca gcaagcttcc
     6841 ttccagttta gcagtaatct acaacaggct tcctttcaac atgataaaga gatgctccaa
     6901 gcacaagttg aggccactaa aaagttgcaa caggaaatga tgaaagtcaa acaggcaatg
     6961 ctcttagaag gtggattctc tgaaacagat gcagcccgtg gggcaatcaa cgcccctatg
     7021 acaaaggctt tggactggag cggaacaagg tactgggccc ctgatgctag gactacaaca
     7081 tacaatgcag gccgtttttc cacccctcaa ccttcggggg cactgccagg aagaatcaat
     7141 cccaggactt ccacccccgc tcggggctcc cctagcacat cttctaatgc ttctactgct
     7201 acttctatat attcaaatca aactgtttca acgagacttg gttctacagc tggttctggc
     7261 accaatgtct cgagtctccc gtcaactgca aggactagga gttgggttga ggatcaaaac
     7321 agaaatttgt cacctttcat gaggggggct cacaacatat cgtttgtcac cccaccatct
     7381 agcagatcct ctagccaagg cacagtctca accgtgccta aagaagtttt ggactcctgg
     7441 actggcgctt tcaacacgcg caggcagcct ctcttcgctc acattcgtag gcgaggggag
     7501 tcacgggtgt aa
//