Typing tool

Complete norovirus genomes

AB447448  GII.4 Asia
 GII.P12

Length: 7,511 | 3 CDS

ORF1: 3..5102
ORF2: 5083..6705
ORF3: 6705..7511
LOCUS       AB447448                7511 bp    RNA     linear   VRL 05-NOV-2008
DEFINITION  Norovirus Hu/GII-4/Sakai2/2006/JP genomic RNA, complete genome.
ACCESSION   AB447448
VERSION     AB447448.1
KEYWORDS    .
SOURCE      Norovirus Hu/GII-4/Sakai2/2006/JP
  ORGANISM  Norovirus Hu/GII-4/Sakai2/2006/JP
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus.
REFERENCE   1
  AUTHORS   Motomura,K., Oka,T., Yokoyama,M., Nakamura,H., Mori,H., Ode,H.,
            Hansman,G.S., Katayama,K., Kanda,T., Tanaka,T., Takeda,N. and
            Sato,H.
  CONSRTM   and the Norovirus Surveillance Group of Japan
  TITLE     Identification of monomorphic and divergent haplotypes in the
            2006-2007 norovirus GII/4 epidemic population by genomewide tracing
            of evolutionary history
  JOURNAL   J. Virol. 82 (22), 11247-11262 (2008)
   PUBMED   18768979
REFERENCE   2  (bases 1 to 7511)
  AUTHORS   Motomura,K. and Sato,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUL-2008) Contact:Kazushi Motomura National Institute
            of Infectious Diseases, Center for Pathogen Genomics; Gakuen 4-7-1,
            Musashi-Murayama, Tokyo 208-0011, Japan
COMMENT     These sequences were determined at our laboratory.
FEATURES             Location/Qualifiers
     source          1..7511
                     /organism="Norovirus Hu/GII-4/Sakai2/2006/JP"
                     /mol_type="genomic RNA"
                     /strain="Hu/GII-4/Sakai2/2006/JP"
                     /isolation_source="stool"
                     /db_xref="taxon:546972"
                     /country="Japan:Sakai"
     CDS             3..5102
                     /note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
                     3Dpol"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="BAG70490.1"
                     /translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARH
                     KQPPPRETPQRPPRPPTPELAKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPD
                     ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
                     LAKVELAPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
                     WLCRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
                     VRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
                     LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
                     KKEEANELAMVRSIEDAVLDLEAIENNHMTALLKDKDSLATYMRTLDLEEEKARKLST
                     KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLAREL
                     AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
                     PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
                     AKRDFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
                     SGLLHERLDEYELQGPTPTTFNFDRNKVLAFRQLAAENKYGLLDTMRVGKQLKDVKTM
                     PELKQALKDVAIKNCQIVYGGCTYRLESDGKGDVKVDRVQSATVQTNNELVGALHHLR
                     CARIRYYVKCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVEDTEETASNDGC
                     PKPKDDDEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
                     KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
                     TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERLNFEAPPSIWSRIVNFGSGWGFWVSP
                     SLFITSTHVIPQGAQEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
                     TVVTLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
                     CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
                     PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
                     RGKPPKPSVLEAAKKTIVNVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCW
                     NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
                     ATMIRCARAFGGLMEELKAHCVTLPVRVGMNMNEDGPIIFERHSRYKYHYDADYSRWD
                     STQQRAVLAAALEIMVKFSPEPHLAQKVAEDLLSPSVMDVGDFKISINEGLPSGVPCT
                     SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
                     EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
                     NHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
                     PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
     CDS             5083..6705
                     /codon_start=1
                     /product="VP1"
                     /protein_id="BAG70491.1"
                     /translation="MKMASNDASPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
                     QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
                     FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
                     VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
                     TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
                     QLSPVNICTFRGDVTHIPGTRTYRMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
                     TQTTKGDGSTRGHKATVSTGSVDFTPKLGSVQFATDTDNDFETGQNTRFTPVGVIQDG
                     SSTHRNEPQQWVLPDYSGRTAHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
                     CLLPQEWVQHFYQEAAPSQSDVALLRFVNPDTGRVLFECKLHKAGYVTVAHTGQHDLV
                     IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
     CDS             6705..7511
                     /codon_start=1
                     /product="VP2"
                     /protein_id="BAG70492.1"
                     /translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
                     SFEFSSNLQQASFQHDKEMLQAQIEATKKLQQGMMKIKQAMLLEGGFSETDAARGAIN
                     APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNPRATVPARGSPSTLS
                     NTSTLTSAYSDQTVSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNV
                     SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN      
        1 gaatgaagat ggcgtctaac gacgcttccg ctgccgctgt tgctaacagc aacaacgaca
       61 ccgcaaaatc ttcaagtgac ggagtgcttt ctagcatggc tgtcactttt aaacgagccc
      121 tcggggcgcg gcacaaacag cctcccccga gggaaacacc acaaagacct ccacgaccac
      181 ccaccccgga acttgccaaa aagatccctc ctcccccacc caacggggag gatgaactag
      241 tggtttctta cagcgccaaa gatggcgttt ccggtttgcc tgagcttacc actgtccggc
      301 agccggatga aaccaacacg gcgttcagtg ttcccccact caaccagagg gagaataggg
      361 acgccaagga gccgctaacc ggaacaatcc tggaaatgtg ggacggggag atctatcatt
      421 acggtctgta tgtggaacga ggccttgtac ttggtgtgca caaaccacca gctgccatca
      481 gcctcgccaa ggttgagcta gcaccactct ctctgttttg gagaccagtg tatacaccac
      541 agtatctcat ctctccagac actctcagga gactgcatgg agagtcgttc ccctacacag
      601 cctttgacaa caactgctat gccttctgct gttgggtcct ggacctaaac gactcgtggt
      661 tgtgcaggag gatgatccag aggacaactg gtttcttcag accttaccaa gactggaaca
      721 ggaaacccct ccccaccatg gatgactcca aactgaagaa ggtggccaac atattcttgt
      781 gtgcgctatc ttcactattc actaggccca tcaaagacat aataggaaag gtgagaccgc
      841 ttaacatcct taacatcttg gcctcatgtg attggacttt tgcaggcata gtggaatctt
      901 tgatcctctt ggcagagctc tttggagttt tctggacacc cccagatgtg tctgcgatga
      961 tcgccccctt actaggtgac tacgaactgc aggggcccga ggaccttgca gtggaactcg
     1021 ttccagtagt gatggggggg attggtttgg tgctaggatt caccaaagag aagatcggaa
     1081 aaatgttgtc atctgctgca tccaccttaa gggcttgtaa agaccttggt gcatacggac
     1141 tggaaatcct aaaattggtc atgaagtggt tcttcccaaa gaaagaggaa gcaaatgagt
     1201 tggctatggt gaggtccatc gaggatgcgg tgctggacct cgaagcaatt gagaacaatc
     1261 acatgactgc cctcctcaaa gacaaagaca gcttggcaac ctatatgaga acccttgacc
     1321 tcgaggagga gaaggccagg aagctttcga ccaagtctgc ttcacctgac atcgtgggca
     1381 caatcaacgc tctcctggcg agaatcgccg ctgcacgctc cctggtgcat cgggcgaaag
     1441 aggaactctc cagcagacca agacctgttg ttgttatgat atcaggcagg ccagggatag
     1501 ggaaaactca ccttgctagg gaactggcca agaaaatcgc agcttcgctt acaggggacc
     1561 agcgtgtggg tctcatccct cgcaatggcg ttgaccactg ggatgcatat aagggggaaa
     1621 gagtcgtcct atgggacgat tatggaatga gtaatcccat ccacgacgcc ctcaggttac
     1681 aggaacttgc tgacacctgc cccctcacgc taaactgtga caggattgag aacaaaggaa
     1741 aggtctttga cagtgatgcc ataatcatca ccactaatct ggccaaccca gcaccattgg
     1801 actatgtcaa ctttgaagcg tgctcgaggc gcatcgactt cctcgtgtac gcagaagccc
     1861 ctgaggtcga gaaggcaaag cgtgatttcc caggtcaacc tgacatgtgg aagaacgcat
     1921 tcagttctga cttctcgcac ataaaactga cgctggctcc gcaaggtggc ttcgacaaga
     1981 acggaaacac cccacacggg aaaggcgtca tgaaaaccct caccactggt tctctcatcg
     2041 cccgagcatc agggctactc catgagaggt tagatgagta tgagctgcag ggcccaaccc
     2101 ctaccacctt taactttgac cgcaacaagg tgcttgcgtt cagacagctt gctgccgaaa
     2161 acaagtacgg gttgttggac acaatgagag ttggaaaaca gctcaaggat gtcaagacca
     2221 tgccagagct caaacaagcg ctcaaagatg tcgcaatcaa gaattgtcag atagtgtatg
     2281 gtggctgcac ttacaggctt gagtctgatg gcaagggtga tgtgaaagtt gacagagttc
     2341 agagcgccac tgtacagacc aacaatgagc ttgtcggcgc cctacatcat cttaggtgtg
     2401 ccagaatcag atattatgtc aagtgtgtcc aggaggccct gtattccatc atccaaattg
     2461 ctggagctgc atttgtaacc acgcgcattg tcaagcgcat gaacatacaa gacctctggt
     2521 ccaagccaca ggtggaggac acagaggaga ctgctagcaa tgatgggtgc ccaaaaccta
     2581 aggatgacga cgagttcgtg gtctcatccg atgacatcaa aaccgagggc aagaaaggga
     2641 agaacaagtc tggccgtggt aagaagcaca cagcattctc aagcaaaggt ctcagtgatg
     2701 aagagtacga tgagtacaaa agaatcagag aagaaaggaa cggcaaatac tccatagagg
     2761 aataccttca ggacagagat aagtattatg aggaggtggc catcgccagg gcgaccgaag
     2821 aggacttctg tgaagaagaa gaggccaaga tccgacaaag gattttcagg ccaacaagga
     2881 aacaacgcaa agaggagagg gcctctctcg gtttggtcac aggctctgaa atcaggaaga
     2941 ggaacccaga cgacttcaag cctaaaggaa agctgtgggc tgatgatgac aggagtgttg
     3001 actacaatga gagactcaat tttgaagccc caccaagcat ctggtcgagg atagtcaatt
     3061 ttggttcggg ttggggcttt tgggtttccc ccagcctgtt cataacatca actcatgtga
     3121 taccccaggg cgcacaggag ttctttggtg ttcccatcaa acaaattcag atacacaaat
     3181 cgggtgaatt ctgtcgtttg aggtttccaa aaccaatcag aactgacgtg acaggcatga
     3241 tcttagaaga aggtgcaccc gaagggaccg tggtcacact actcattaag aggccaactg
     3301 gagaactcat gcccttggca gccagaatgg gaacccatgc aaccatgaag attcaagggc
     3361 gcactgttgg aggtcaaatg ggcatgctcc taacaggatc caacgccaag agtatggacc
     3421 tgggcaccac accaggtgac tgtggttgtc cctacattta caagaggggg aatgactatg
     3481 tagtcattgg agtccacaca gctgccgccc gtggaggaaa cactgtcata tgtgccaccc
     3541 aagggagcga gggagaagcc acacttgaag gcggtgacag caaggggacc tactgcggtg
     3601 caccaatctt aggtccagga agtgccccga agctcagcac caagactaaa ttctggagat
     3661 catccacggc accactccca cctggtacct atgagccagc ctacctcggc ggcaaggacc
     3721 ccagagttaa gggtggccct tcattgcaac aagttatgag ggaccagctg aaaccattca
     3781 ctgaacccag gggtaaacca ccaaaaccaa gtgtgttaga agctgccaag aaaaccatcg
     3841 tcaatgtcct tgaacaaaca attgatccac ctcaaaaatg gtcatttgcg caggcatgcg
     3901 catcccttga caagaccact tccagtggtc acccgcacca catgcggaaa aacgactgct
     3961 ggaacgggga atcctttaca ggcaaattgg cagaccaggc ttccaaggcc aacctgatgt
     4021 tcgaggaggg aaagaacatg actccagtct acacgggtgc gcttaaggac gagctggtca
     4081 agactgacaa aatttatggc aagatcaaaa agaggcttct ctggggttcg gacctggcga
     4141 ccatgatccg gtgcgctcga gcatttgggg gcctgatgga ggaactcaaa gcacattgtg
     4201 tcacactacc tgtcagagtg ggtatgaata tgaatgagga tggtcctatc atctttgaga
     4261 gacactctag atataaatat cattatgatg ctgattactc ccggtgggac tcaacacaac
     4321 aaagagccgt gttagcagcg gctttagaaa tcatggtcaa gttctcccca gagccgcatc
     4381 tggcccaaaa ggttgcagaa gaccttcttt ctcccagcgt gatggacgtg ggtgatttca
     4441 aaatatcaat caatgagggt ctcccctccg gggtgccctg cacctcccaa tggaattcca
     4501 tcgcccactg gctcctcact ctatgtgcac tctctgaggt tacaaacctg tcccctgaca
     4561 ttatccaggc caactctctc ttttctttct acggtgatga tgaaattgtg agcacagaca
     4621 taaaattgga cccagaaaag ctgacagcaa aactcaagga atacgggtta aaaccgaccc
     4681 gccctgacaa gactgaggga ccccttgtca tctctgaaga cctgaatggc ctaaccttcc
     4741 tgcggagaac cgtgacccgc gacccagcag gctggtttgg aaagttggaa cagagttcaa
     4801 tactcagaca aatgtattgg actagaggcc ccaaccatga agacccatct gaaacaatga
     4861 taccacactc ccagaggccc atacaattga tgtctttgct gggtgaggct gcactccacg
     4921 gcccagcatt ctacagcaaa atcagcaaac tggtcattgc agagttgaag gaaggtggca
     4981 tggattttta cgtgccaaga caagagccaa tgttcagatg gatgagattc tcggatctga
     5041 gcacgtggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat
     5101 gacgccagcc catctgatgg gtccacagcc aacctcgtcc cagaggtcaa caatgaggtt
     5161 atggctttgg agcccgttgt tggtgccgct attgcggcgc ctgtagcggg ccaacaaaat
     5221 gtaattgacc cctggattag aaataatttt gtacaagccc ctggtggaga gttcacagta
     5281 tcccctagaa acgctccagg tgaaatacta tggagcgcgc ccttaggccc tgatctgaat
     5341 ccataccttt ctcacctggc cagaatgtac aatggttatg caggtggttt tgaagtgcag
     5401 gtaatcctcg cggggaacgc gttcaccgcc gggaaaatca tatttgcagc agtcccacca
     5461 aatttcccaa ctgaaggctt gagccccagc caggtcacta tgttccccca cataatagta
     5521 gatgttaggc aattggaacc tgtgttgatc cccttacctg atgttaggaa caatttctac
     5581 cattacaatc aatcaaacga ctccaccatt aaattgatag caatgctgta cacaccactt
     5641 agggctaata atgctgggga tgatgtcttc acagtctctt gtcgagtcct cacgaggcca
     5701 tcccccgatt ttgatttcat atttctggtg ccacccacag ttgagtcaag aaccaaacca
     5761 ttcaccgtcc caattttaac tgttgaggaa atgaccaatt caagatttcc cattcctttg
     5821 gaaaaattgt tcacgggtcc cagcagtgcc tttgtcgtcc aaccacaaaa tggcaggtgc
     5881 acgactgatg gcgtgctctt aggcactacc caactgtccc ccgtcaacat ctgcaccttc
     5941 agaggagatg tcacccacat tccaggtact cgtacttaca gaatgaattt ggcttctcaa
     6001 aattggaaca attatgaccc aacagaagaa atcccagccc ctctgggaac tccagatttc
     6061 gtgggaaaga tccaaggcat gctcacccaa accacaaagg gagacggctc gacccgcggt
     6121 cacaaagcta cagtgagcac tgggagtgtt gacttcactc caaagctggg cagcgttcag
     6181 ttcgccactg acacagacaa tgattttgaa actggccaaa acacaaggtt caccccagtc
     6241 ggtgtcatcc aggatggtag tagtacccac agaaatgaac cccaacaatg ggtactccca
     6301 gattactcag gtagaactgc tcataatgta cacctggccc ctgccgtagc ccccactttt
     6361 ccgggtgagc aacttctttt cttcagatct actatgcccg gatgcagtgg gtatcccaat
     6421 atggatttgg attgtctact cccccaggaa tgggtgcagc acttctacca agaggcagcc
     6481 ccatcacaat ctgacgtggc tttgttgaga tttgtgaatc cagacacagg tagggttctg
     6541 tttgagtgca agcttcataa agcaggctat gtcacagtgg ctcacactgg ccagcatgat
     6601 ttggtcatcc cccccaatgg ctactttaga tttgattcct gggtcaacca gttctacaca
     6661 cttgccccca tgggaaatgg agcggggcgt agacgtgcat tataatggct ggagctttct
     6721 ttgctggatt ggcatctgat gtccttggct ctggacttgg ttccctgatc aatgctgggg
     6781 ctggggccat caaccaaaaa gttgaatttg aaaataacag aaaattgcaa caagcttcct
     6841 tcgaatttag cagcaatcta caacaggctt cctttcaaca tgacaaagag atgctccaag
     6901 cacaaattga ggccactaaa aagttacagc agggtatgat gaaaatcaaa caggcaatgc
     6961 tcctagaggg tggattctct gaaacagatg cggcccgtgg ggcaatcaac gcccccatga
     7021 caaaggcttt ggactggagc ggaacaaggt actgggctcc tgatgctaga accacaacat
     7081 acaatgcagg ccgtttttcc acccctcaac cttcgggggc attgccagga agaactaatc
     7141 ccagggctac tgtacccgct cggggctccc ccagcacact ttctaatact tccactctta
     7201 cttctgccta ttcagatcaa actgtttcaa cgagacttgg ttctacagct ggttctggca
     7261 ccagtgtctc gagtctcccg tcaactgcaa ggactaggag ttgggttgag gatcaaaaca
     7321 ggaatttgtc acctttcatg aggggggctc acaacgtatc gttcgtcacc ccaccatcta
     7381 gtagatcctc tagccaaggc acagtctcga ccgtgcccaa agaagttttg gactcctgga
     7441 ctggcgcttt caacacgcgc aggcagcctc tcttcgctca cattcgtaag cgaggggagt
     7501 cacgggtgta a
//